BDBM50279557 9-hydroxy-6-(3-(phenylamino)propyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL483800

SMILES: Oc1ccc2n(CCCNc3ccccc3)c3ccc4C(=O)NC(=O)c4c3c2c1

InChI Key: InChIKey=WRJJTOFYAHDGGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279557 (9-hydroxy-6-(3-(phenylamino)propyl)pyrrolo[3,4-c]c...) Show SMILES Oc1ccc2n(CCCNc3ccccc3)c3ccc4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C23H19N3O3/c27-15-7-9-18-17(13-15)20-19(10-8-16-21(20)23(29)25-22(16)28)26(18)12-4-11-24-14-5-2-1-3-6-14/h1-3,5-10,13,24,27H,4,11-12H2,(H,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair