BDBM50279700 1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-(4-(4-methylpiperazin-1-yl)butyl)imidazolidine-2,4-dione::CHEMBL475109

SMILES: COc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCN(C)CC4)c3=O)c2c1

InChI Key: InChIKey=FUNXQWLTAVXFNR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Cavia porcellus)	BDBM50279700 (1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...) Show SMILES COc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCN(C)CC4)c3=O)c2c1 |w:10.10| Show InChI InChI=1S/C22H31N5O4/c1-24-10-12-25(13-11-24)8-3-4-9-26-21(28)16-27(22(26)29)23-19-7-14-31-20-6-5-17(30-2)15-18(19)20/h5-6,15-16,28H,3-4,7-14H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp tech...				Bioorg Med Chem Lett 19: 1477-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.022 BindingDB Entry DOI: 10.7270/Q22J6BQK
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv7.1 (Cavia porcellus)	BDBM50279700 (1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...) Show SMILES COc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCN(C)CC4)c3=O)c2c1 |w:10.10| Show InChI InChI=1S/C22H31N5O4/c1-24-10-12-25(13-11-24)8-3-4-9-26-21(28)16-27(22(26)29)23-19-7-14-31-20-6-5-17(30-2)15-18(19)20/h5-6,15-16,28H,3-4,7-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...				Bioorg Med Chem Lett 19: 1477-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.022 BindingDB Entry DOI: 10.7270/Q22J6BQK
					More data for this Ligand-Target Pair