BindingDB logo
myBDB logout

null

SMILES: CCCOc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCN(C)CC4)c3=O)c2c1

InChI Key: InChIKey=FQZKLEKBTLZEOA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279702   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Cavia porcellus)
BDBM50279702
PNG
(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)
Show SMILES CCCOc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCN(C)CC4)c3=O)c2c1 |w:12.12|
Show InChI InChI=1S/C24H35N5O4/c1-3-15-32-19-6-7-22-20(17-19)21(8-16-33-22)25-29-18-23(30)28(24(29)31)10-5-4-9-27-13-11-26(2)12-14-27/h6-7,17-18,30H,3-5,8-16H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.18E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp tech...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1


(Cavia porcellus)
BDBM50279702
PNG
(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)
Show SMILES CCCOc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCN(C)CC4)c3=O)c2c1 |w:12.12|
Show InChI InChI=1S/C24H35N5O4/c1-3-15-32-19-6-7-22-20(17-19)21(8-16-33-22)25-29-18-23(30)28(24(29)31)10-5-4-9-27-13-11-26(2)12-14-27/h6-7,17-18,30H,3-5,8-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.28E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair