BDBM50279824 (S)-1-((R)-3,3,3-Trifluoro-2-mercaptomethyl-propionyl)-pyrrolidine-2-carboxylic acid::CHEMBL347388

SMILES: OC(=O)[C@@H]1CCCN1C(=O)[C@@H](CS)C(F)(F)F

InChI Key: InChIKey=PPHPDJQYQOXIEP-RITPCOANSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50279824 ((S)-1-((R)-3,3,3-Trifluoro-2-mercaptomethyl-propio...) Show SMILES OC(=O)[C@@H]1CCCN1C(=O)[C@@H](CS)C(F)(F)F Show InChI InChI=1S/C9H12F3NO3S/c10-9(11,12)5(4-17)7(14)13-3-1-2-6(13)8(15)16/h5-6,17H,1-4H2,(H,15,16)/t5-,6+/m1/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity was evaluated against angiotensin converting enzyme from rabbit in bovine buffered base				Bioorg Med Chem Lett 1: 581-584 (1991) Article DOI: 10.1016/S0960-894X(01)81155-0 BindingDB Entry DOI: 10.7270/Q2GF0TZX
					More data for this Ligand-Target Pair