null

SMILES: COC(=O)Nc1cn2nc(OCc3cc(OC)c(OC)c(OC)c3)ccc2n1

InChI Key: InChIKey=UMSHZWFCVXIDEO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50280140 (CHEMBL418565 | [6-(3,4,5-Trimethoxy-benzyloxy)-imi...) Show SMILES COC(=O)Nc1cn2nc(OCc3cc(OC)c(OC)c(OC)c3)ccc2n1 Show InChI InChI=1S/C18H20N4O6/c1-24-12-7-11(8-13(25-2)17(12)26-3)10-28-16-6-5-15-19-14(9-22(15)21-16)20-18(23)27-4/h5-9H,10H2,1-4H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for competitive inhibition with radioligand [3H]colchicine at colchicine site of mammalian tubulin				Bioorg Med Chem Lett 2: 1257-1262 (1992) Article DOI: 10.1016/S0960-894X(00)80225-5 BindingDB Entry DOI: 10.7270/Q25X29DB
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50280140 (CHEMBL418565 | [6-(3,4,5-Trimethoxy-benzyloxy)-imi...) Show SMILES COC(=O)Nc1cn2nc(OCc3cc(OC)c(OC)c(OC)c3)ccc2n1 Show InChI InChI=1S/C18H20N4O6/c1-24-12-7-11(8-13(25-2)17(12)26-3)10-28-16-6-5-15-19-14(9-22(15)21-16)20-18(23)27-4/h5-9H,10H2,1-4H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro mammalian brain tubulin polymerization using standard assay.				Bioorg Med Chem Lett 2: 1257-1262 (1992) Article DOI: 10.1016/S0960-894X(00)80225-5 BindingDB Entry DOI: 10.7270/Q25X29DB
					More data for this Ligand-Target Pair