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SMILES: O=C1N(C[C@@H]2C[C@@H]2CN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12

InChI Key: InChIKey=KNTNKMFODKUWSB-CVEARBPZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280296   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Mus musculus (Mouse))		BDBM50280296
PNG
(1,1-Dioxo-2-[(1R,2S)-2-(4-pyrimidin-2-yl-piperazin...)
Show SMILES O=C1N(C[C@@H]2C[C@@H]2CN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12
Show InChI InChI=1S/C20H23N5O3S/c26-19-17-4-1-2-5-18(17)29(27,28)25(19)14-16-12-15(16)13-23-8-10-24(11-9-23)20-21-6-3-7-22-20/h1-7,15-16H,8-14H2/t15-,16+/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
 44n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as a radioligand

Bioorg Med Chem Lett 2: 1703-1706 (1992)


Article DOI: 10.1016/S0960-894X(00)80460-6
BindingDB Entry DOI: 10.7270/Q25M65N7
More data for this
Ligand-Target Pair