BDBM50280332 4,4-Diethyl-6-[2-oxo-prop-(E)-ylidene]-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-piperidin-2-one::CHEMBL52046

SMILES: CCC1(CC)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(C1)=CC(C)=O

InChI Key: InChIKey=OVPPUEXRZRWEHI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50280332 (4,4-Diethyl-6-[2-oxo-prop-(E)-ylidene]-1-[2'-(1H-t...) Show SMILES CCC1(CC)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(C1)=CC(C)=O |w:29.33| Show InChI InChI=1S/C26H29N5O2/c1-4-26(5-2)15-21(14-18(3)32)31(24(33)16-26)17-19-10-12-20(13-11-19)22-8-6-7-9-23(22)25-27-29-30-28-25/h6-14H,4-5,15-17H2,1-3H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair