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SMILES: C(CCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)CCn1cccn1

InChI Key: InChIKey=CMAZWLURLJPZQB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50280422 (1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...) Show SMILES C(CCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)CCn1cccn1 Show InChI InChI=1S/C23H24N4S/c1-4-11-19(12-5-1)21-22(20-13-6-2-7-14-20)26-23(25-21)28-18-9-3-8-16-27-17-10-15-24-27/h1-2,4-7,10-15,17H,3,8-9,16,18H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liver				Bioorg Med Chem Lett 2: 375-380 (1992) Article DOI: 10.1016/S0960-894X(00)80149-3 BindingDB Entry DOI: 10.7270/Q2MP535G
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50280422 (1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...) Show SMILES C(CCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)CCn1cccn1 Show InChI InChI=1S/C23H24N4S/c1-4-11-19(12-5-1)21-22(20-13-6-2-7-14-20)26-23(25-21)28-18-9-3-8-16-27-17-10-15-24-27/h1-2,4-7,10-15,17H,3,8-9,16,18H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liver				Bioorg Med Chem Lett 2: 375-380 (1992) Article DOI: 10.1016/S0960-894X(00)80149-3 BindingDB Entry DOI: 10.7270/Q2MP535G
					More data for this Ligand-Target Pair