null

SMILES: Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1

InChI Key: InChIKey=CRQHLFRDYLIVLG-UHFFFAOYSA-L

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280448 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H13F3N5O4P/c15-10(14(16,17)27(24,25)26)8-4-2-1-3-7(8)5-22-6-19-9-11(22)20-13(18)21-12(9)23/h1-4,6,10H,5H2,(H2,24,25,26)(H3,18,20,21,23)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280448 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H13F3N5O4P/c15-10(14(16,17)27(24,25)26)8-4-2-1-3-7(8)5-22-6-19-9-11(22)20-13(18)21-12(9)23/h1-4,6,10H,5H2,(H2,24,25,26)(H3,18,20,21,23)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50280448 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H13F3N5O4P/c15-10(14(16,17)27(24,25)26)8-4-2-1-3-7(8)5-22-6-19-9-11(22)20-13(18)21-12(9)23/h1-4,6,10H,5H2,(H2,24,25,26)(H3,18,20,21,23)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50280448 (2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)met...) Show SMILES Nc1nc2n(Cc3ccccc3C(F)C(F)(F)P([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C14H13F3N5O4P/c15-10(14(16,17)27(24,25)26)8-4-2-1-3-7(8)5-22-6-19-9-11(22)20-13(18)21-12(9)23/h1-4,6,10H,5H2,(H2,24,25,26)(H3,18,20,21,23)/p-2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonate				Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N
					More data for this Ligand-Target Pair