BDBM50280521 (4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-2-yl)-allyl]-dihydro-furan-2-one::CHEMBL22923

SMILES: C[C@@H]1OC(=O)C[C@H]1C\C=C\[C@H]1CCCCN1C

InChI Key: InChIKey=GWRXGSVCPYKRNL-CAJTZJJPSA-N

Data: 5 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50280521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50280521 ((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...) Show SMILES C[C@@H]1OC(=O)C[C@H]1C\C=C\[C@H]1CCCCN1C Show InChI InChI=1S/C14H23NO2/c1-11-12(10-14(16)17-11)6-5-8-13-7-3-4-9-15(13)2/h5,8,11-13H,3-4,6-7,9-10H2,1-2H3/b8-5+/t11-,12+,13+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant of the compound for human Muscarinic acetylcholine receptor M2 was determined.				Bioorg Med Chem Lett 2: 797-802 (1992) Article DOI: 10.1016/S0960-894X(00)80534-X BindingDB Entry DOI: 10.7270/Q22R3RKP
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50280521 ((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...) Show SMILES C[C@@H]1OC(=O)C[C@H]1C\C=C\[C@H]1CCCCN1C Show InChI InChI=1S/C14H23NO2/c1-11-12(10-14(16)17-11)6-5-8-13-7-3-4-9-15(13)2/h5,8,11-13H,3-4,6-7,9-10H2,1-2H3/b8-5+/t11-,12+,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant for the blocking of brainstem muscarinic M2 receptor was reported.				Bioorg Med Chem Lett 2: 797-802 (1992) Article DOI: 10.1016/S0960-894X(00)80534-X BindingDB Entry DOI: 10.7270/Q22R3RKP
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50280521 ((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...) Show SMILES C[C@@H]1OC(=O)C[C@H]1C\C=C\[C@H]1CCCCN1C Show InChI InChI=1S/C14H23NO2/c1-11-12(10-14(16)17-11)6-5-8-13-7-3-4-9-15(13)2/h5,8,11-13H,3-4,6-7,9-10H2,1-2H3/b8-5+/t11-,12+,13+/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-QNB from muscarinic receptor 1 expressed in CHO-K1 cells				Bioorg Med Chem Lett 3: 1247-1252 (1993) Article DOI: 10.1016/S0960-894X(00)80325-X BindingDB Entry DOI: 10.7270/Q2348K91
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50280521 ((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...) Show SMILES C[C@@H]1OC(=O)C[C@H]1C\C=C\[C@H]1CCCCN1C Show InChI InChI=1S/C14H23NO2/c1-11-12(10-14(16)17-11)6-5-8-13-7-3-4-9-15(13)2/h5,8,11-13H,3-4,6-7,9-10H2,1-2H3/b8-5+/t11-,12+,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)				Bioorg Med Chem Lett 3: 1247-1252 (1993) Article DOI: 10.1016/S0960-894X(00)80325-X BindingDB Entry DOI: 10.7270/Q2348K91
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50280521 ((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...) Show SMILES C[C@@H]1OC(=O)C[C@H]1C\C=C\[C@H]1CCCCN1C Show InChI InChI=1S/C14H23NO2/c1-11-12(10-14(16)17-11)6-5-8-13-7-3-4-9-15(13)2/h5,8,11-13H,3-4,6-7,9-10H2,1-2H3/b8-5+/t11-,12+,13+/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dissociation constant of the compound for human Muscarinic acetylcholine receptor M1 was determined.				Bioorg Med Chem Lett 2: 797-802 (1992) Article DOI: 10.1016/S0960-894X(00)80534-X BindingDB Entry DOI: 10.7270/Q22R3RKP
					More data for this Ligand-Target Pair