null
SMILES: O=C(CN1CCN(CCCCCCCCCCNC(=S)Nc2cccc(c2)N=C=S)CC1)N1c2ccccc2C(=O)Nc2cccnc12
InChI Key: InChIKey=UKSAODFPXKRIDP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50280622 (1-(3-Isothiocyanato-phenyl)-3-(4-{4-[2-oxo-2-(6-ox...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated for irreversible inhibition at rat forebrain muscarinic receptor | Bioorg Med Chem Lett 2: 845-850 (1992) Article DOI: 10.1016/S0960-894X(00)80542-9 BindingDB Entry DOI: 10.7270/Q2F18ZMP | |||||||||||
More data for this Ligand-Target Pair |