BDBM50280712 CHEMBL14819::Sodium; 3-{1-[3-(7-chloro-quinolin-2-ylmethoxy)-phenyl]-3-[2-(2H-[1,2,4]triazol-3-yl)-phenyl]-propylsulfanyl}-propionate

SMILES: [O-]C(=O)CCSC(CCc1ccccc1-c1nnc[nH]1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1

InChI Key: InChIKey=NAVMHFVFGUAGPV-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280712 (CHEMBL14819 | Sodium; 3-{1-[3-(7-chloro-quinolin-2...) Show SMILES [O-]C(=O)CCSC(CCc1ccccc1-c1nnc[nH]1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C30H27ClN4O3S/c31-23-11-8-21-9-12-24(34-27(21)17-23)18-38-25-6-3-5-22(16-25)28(39-15-14-29(36)37)13-10-20-4-1-2-7-26(20)30-32-19-33-35-30/h1-9,11-12,16-17,19,28H,10,13-15,18H2,(H,36,37)(H,32,33,35)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
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