BDBM50280869 13-methyl-12-propyl-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::CHEMBL59054

SMILES: CCCn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12

InChI Key: InChIKey=JWKXCNVBQKKSDL-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-Dependent Protein Kinase (Bos taurus (bovine))	BDBM50280869 (13-methyl-12-propyl-6,7,12,13-tetrahydro-5H-indolo...) Show SMILES CCCn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C24H21N3O/c1-3-12-27-18-11-7-5-9-15(18)19-16-13-25-24(28)21(16)20-14-8-4-6-10-17(14)26(2)22(20)23(19)27/h4-11H,3,12-13H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for inhibitory activity against cGMP-dependent protein kinase from bovine lung (G-kinase)				Bioorg Med Chem Lett 3: 1959-1964 (1993) Article DOI: 10.1016/S0960-894X(01)80995-1 BindingDB Entry DOI: 10.7270/Q2QC03DJ
					More data for this Ligand-Target Pair
Protein kinase C (PKC) (Rattus norvegicus-Rattus norvegicus (Rat)-Rattus n...)	BDBM50280869 (13-methyl-12-propyl-6,7,12,13-tetrahydro-5H-indolo...) Show SMILES CCCn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C24H21N3O/c1-3-12-27-18-11-7-5-9-15(18)19-16-13-25-24(28)21(16)20-14-8-4-6-10-17(14)26(2)22(20)23(19)27/h4-11H,3,12-13H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for inhibitory activity against protein kinase C from rat brain				Bioorg Med Chem Lett 3: 1959-1964 (1993) Article DOI: 10.1016/S0960-894X(01)80995-1 BindingDB Entry DOI: 10.7270/Q2QC03DJ
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM50280869 (13-methyl-12-propyl-6,7,12,13-tetrahydro-5H-indolo...) Show SMILES CCCn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C24H21N3O/c1-3-12-27-18-11-7-5-9-15(18)19-16-13-25-24(28)21(16)20-14-8-4-6-10-17(14)26(2)22(20)23(19)27/h4-11H,3,12-13H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for inhibitory activity against myosin light-chain kinase from chicken gizzard (M-kinase)				Bioorg Med Chem Lett 3: 1959-1964 (1993) Article DOI: 10.1016/S0960-894X(01)80995-1 BindingDB Entry DOI: 10.7270/Q2QC03DJ
					More data for this Ligand-Target Pair
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM50280869 (13-methyl-12-propyl-6,7,12,13-tetrahydro-5H-indolo...) Show SMILES CCCn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C24H21N3O/c1-3-12-27-18-11-7-5-9-15(18)19-16-13-25-24(28)21(16)20-14-8-4-6-10-17(14)26(2)22(20)23(19)27/h4-11H,3,12-13H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for inhibitory activity against cAMP-dependent protein kinase from bovine heart (A-kinase)				Bioorg Med Chem Lett 3: 1959-1964 (1993) Article DOI: 10.1016/S0960-894X(01)80995-1 BindingDB Entry DOI: 10.7270/Q2QC03DJ
					More data for this Ligand-Target Pair