BDBM50280987 1N-[12-isopropyl-2,6-dimethyltricyclo[8.4.0.02,7]tetradeca-1(14),10,12-trien-6-ylmethyl]-1,4-pentanediamine::CHEMBL545218

SMILES: CC(N)CCCNC[C@]1(C)CCC[C@@]2(C)C1CCc1cc(ccc21)C(C)C

InChI Key: InChIKey=ZBINKVYSDZCYDZ-JYIDCXNYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50280987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2, major isoenzyme (Sus scrofa (pig))	BDBM50280987 (1N-[12-isopropyl-2,6-dimethyltricyclo[8.4.0.02,7]t...) Show SMILES CC(N)CCCNC[C@]1(C)CCC[C@@]2(C)C1CCc1cc(ccc21)C(C)C |r| Show InChI InChI=1S/C25H42N2/c1-18(2)20-9-11-22-21(16-20)10-12-23-24(4,13-7-14-25(22,23)5)17-27-15-6-8-19(3)26/h9,11,16,18-19,23,27H,6-8,10,12-15,17,26H2,1-5H3/t19?,23?,24-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its inhibitory activity against Phospholipase A2 (PLA2)				Bioorg Med Chem Lett 3: 2087-2092 (1993) Article DOI: 10.1016/S0960-894X(01)81022-2 BindingDB Entry DOI: 10.7270/Q2G73F6K
					More data for this Ligand-Target Pair
Cyclooxygenase (Bos taurus)	BDBM50280987 (1N-[12-isopropyl-2,6-dimethyltricyclo[8.4.0.02,7]t...) Show SMILES CC(N)CCCNC[C@]1(C)CCC[C@@]2(C)C1CCc1cc(ccc21)C(C)C |r| Show InChI InChI=1S/C25H42N2/c1-18(2)20-9-11-22-21(16-20)10-12-23-24(4,13-7-14-25(22,23)5)17-27-15-6-8-19(3)26/h9,11,16,18-19,23,27H,6-8,10,12-15,17,26H2,1-5H3/t19?,23?,24-,25+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its inhibitory activity against PGS (prostaglandin synthetase).				Bioorg Med Chem Lett 3: 2087-2092 (1993) Article DOI: 10.1016/S0960-894X(01)81022-2 BindingDB Entry DOI: 10.7270/Q2G73F6K
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50280987 (1N-[12-isopropyl-2,6-dimethyltricyclo[8.4.0.02,7]t...) Show SMILES CC(N)CCCNC[C@]1(C)CCC[C@@]2(C)C1CCc1cc(ccc21)C(C)C |r| Show InChI InChI=1S/C25H42N2/c1-18(2)20-9-11-22-21(16-20)10-12-23-24(4,13-7-14-25(22,23)5)17-27-15-6-8-19(3)26/h9,11,16,18-19,23,27H,6-8,10,12-15,17,26H2,1-5H3/t19?,23?,24-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its inhibitory activity against 5-lipoxygenase				Bioorg Med Chem Lett 3: 2087-2092 (1993) Article DOI: 10.1016/S0960-894X(01)81022-2 BindingDB Entry DOI: 10.7270/Q2G73F6K
					More data for this Ligand-Target Pair