BDBM50281086 (3S,4S)-1,4-Diacetyl-3-butyl-azetidin-2-one::CHEMBL418925

SMILES: CCCC[C@H]1[C@H](N(C(C)=O)C1=O)C(C)=O

InChI Key: InChIKey=IWLSHAKMCNMBMN-VHSXEESVSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pancreatic elastase (Sus scrofa)	BDBM50281086 ((3S,4S)-1,4-Diacetyl-3-butyl-azetidin-2-one | CHEM...) Show SMILES CCCC[C@H]1[C@H](N(C(C)=O)C1=O)C(C)=O Show InChI InChI=1S/C11H17NO3/c1-4-5-6-9-10(7(2)13)12(8(3)14)11(9)15/h9-10H,4-6H2,1-3H3/t9-,10+/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE)				Bioorg Med Chem Lett 3: 2547-2552 (1993) Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW
					More data for this Ligand-Target Pair
Leukocyte elastase (Homo sapiens (Human))	BDBM50281086 ((3S,4S)-1,4-Diacetyl-3-butyl-azetidin-2-one | CHEM...) Show SMILES CCCC[C@H]1[C@H](N(C(C)=O)C1=O)C(C)=O Show InChI InChI=1S/C11H17NO3/c1-4-5-6-9-10(7(2)13)12(8(3)14)11(9)15/h9-10H,4-6H2,1-3H3/t9-,10+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE)				Bioorg Med Chem Lett 3: 2547-2552 (1993) Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW
					More data for this Ligand-Target Pair
Elastase 2A (Rattus norvegicus)	BDBM50281086 ((3S,4S)-1,4-Diacetyl-3-butyl-azetidin-2-one | CHEM...) Show SMILES CCCC[C@H]1[C@H](N(C(C)=O)C1=O)C(C)=O Show InChI InChI=1S/C11H17NO3/c1-4-5-6-9-10(7(2)13)12(8(3)14)11(9)15/h9-10H,4-6H2,1-3H3/t9-,10+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE)				Bioorg Med Chem Lett 3: 2547-2552 (1993) Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW
					More data for this Ligand-Target Pair