BDBM50281089 (3S,4R)-1-Acetyl-3-methoxy-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one::CHEMBL431207

SMILES: CO[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1

InChI Key: InChIKey=QZPDCXJUBPDVED-HOQBHHMFSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50281089 ((3S,4R)-1-Acetyl-3-methoxy-4-((E)-1-methyl-2-pheny...) Show SMILES CO[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C15H17NO3/c1-10(9-12-7-5-4-6-8-12)13-14(19-3)15(18)16(13)11(2)17/h4-9,13-14H,1-3H3/b10-9+/t13-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE)				Bioorg Med Chem Lett 3: 2547-2552 (1993) Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW
					More data for this Ligand-Target Pair
Elastase 2A (Rattus norvegicus)	BDBM50281089 ((3S,4R)-1-Acetyl-3-methoxy-4-((E)-1-methyl-2-pheny...) Show SMILES CO[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C15H17NO3/c1-10(9-12-7-5-4-6-8-12)13-14(19-3)15(18)16(13)11(2)17/h4-9,13-14H,1-3H3/b10-9+/t13-,14+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE)				Bioorg Med Chem Lett 3: 2547-2552 (1993) Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW
					More data for this Ligand-Target Pair
Pancreatic elastase (Sus scrofa)	BDBM50281089 ((3S,4R)-1-Acetyl-3-methoxy-4-((E)-1-methyl-2-pheny...) Show SMILES CO[C@H]1[C@H](N(C(C)=O)C1=O)C(\C)=C\c1ccccc1 Show InChI InChI=1S/C15H17NO3/c1-10(9-12-7-5-4-6-8-12)13-14(19-3)15(18)16(13)11(2)17/h4-9,13-14H,1-3H3/b10-9+/t13-,14+/m1/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE)				Bioorg Med Chem Lett 3: 2547-2552 (1993) Article DOI: 10.1016/S0960-894X(01)80714-9 BindingDB Entry DOI: 10.7270/Q2CV4HNW
					More data for this Ligand-Target Pair