BDBM50281129 (S)-2-{4-[2-(2-Amino-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid::CHEMBL314116

SMILES: Nc1ncc2CC(CCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2n1

InChI Key: InChIKey=DKCUJHQRKRWPFM-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycinamide ribonucleotide formyltransferase (GARFTase) (Homo sapiens (Human))	BDBM50281129 ((S)-2-{4-[2-(2-Amino-5,6,7,8-tetrahydro-pyrido[2,3...) Show SMILES Nc1ncc2CC(CCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2n1 Show InChI InChI=1S/C21H25N5O5/c22-21-24-11-15-9-13(10-23-18(15)26-21)2-1-12-3-5-14(6-4-12)19(29)25-16(20(30)31)7-8-17(27)28/h3-6,11,13,16H,1-2,7-10H2,(H,25,29)(H,27,28)(H,30,31)(H3,22,23,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.86E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for the inhibition of recombinant human monofunctional Glycinamide ribonucleotide formyltransferase				Bioorg Med Chem Lett 3: 2657-2660 (1993) Article DOI: 10.1016/S0960-894X(01)80736-8 BindingDB Entry DOI: 10.7270/Q2R49QPW
					More data for this Ligand-Target Pair
GAR transformylase (Mus musculus)	BDBM50281129 ((S)-2-{4-[2-(2-Amino-5,6,7,8-tetrahydro-pyrido[2,3...) Show SMILES Nc1ncc2CC(CCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2n1 Show InChI InChI=1S/C21H25N5O5/c22-21-24-11-15-9-13(10-23-18(15)26-21)2-1-12-3-5-14(6-4-12)19(29)25-16(20(30)31)7-8-17(27)28/h3-6,11,13,16H,1-2,7-10H2,(H,25,29)(H,27,28)(H,30,31)(H3,22,23,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for the inhibition against the human dihydrofolate reductase				Bioorg Med Chem Lett 3: 2657-2660 (1993) Article DOI: 10.1016/S0960-894X(01)80736-8 BindingDB Entry DOI: 10.7270/Q2R49QPW
					More data for this Ligand-Target Pair