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SMILES: CC(C)(C)OC(=O)NC(C[Si](C)(C)C)C(=O)C(F)(F)C(=O)NCc1ccccc1

InChI Key: InChIKey=DOUQHHUDEOWPSM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281475   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM50281475
PNG
((3-Benzylcarbamoyl-3,3-difluoro-2-oxo-1-trimethyls...)
Show SMILES CC(C)(C)OC(=O)NC(C[Si](C)(C)C)C(=O)C(F)(F)C(=O)NCc1ccccc1
Show InChI InChI=1S/C20H30F2N2O4Si/c1-19(2,3)28-18(27)24-15(13-29(4,5)6)16(25)20(21,22)17(26)23-12-14-10-8-7-9-11-14/h7-11,15H,12-13H2,1-6H3,(H,23,26)(H,24,27)
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MMDB

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PC sid
UniChem

Similars
Article
 2.50E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against the recombinant HIV-1 protease

Bioorg Med Chem Lett 3: 253-258 (1993)


Article DOI: 10.1016/S0960-894X(01)80887-8
BindingDB Entry DOI: 10.7270/Q2RX9C0Q
More data for this
Ligand-Target Pair