BDBM50281521 CHEMBL330866::[3-Methyl-5-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-pyrrolidin-(2Z)-ylidene]-acetic acid ethyl ester
SMILES: CCOC(=O)\C=C1\C(C)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InChI Key: InChIKey=PMOPIBNBQVNSQV-MOSHPQCFSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin II type 1a (AT-1a) receptor (Bos taurus) | BDBM50281521 (CHEMBL330866 | [3-Methyl-5-oxo-1-[2'-(1H-tetrazol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem... | Bioorg Med Chem Lett 3: 369-374 (1993) Article DOI: 10.1016/S0960-894X(01)80914-8 BindingDB Entry DOI: 10.7270/Q20G3K2H | |||||||||||
More data for this Ligand-Target Pair |