BDBM50281523 CHEMBL421094::[3-Oxo-2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-aza-spiro[4.4]non-(1Z)-ylidene]-acetic acid ethyl ester

SMILES: CCOC(=O)\C=C1/N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(=O)CC11CCCC1

InChI Key: InChIKey=UPFPNGZNCQRTJY-JCMHNJIXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (Bos taurus)	BDBM50281523 (CHEMBL421094 | [3-Oxo-2-[2'-(1H-tetrazol-5-yl)-bip...) Show SMILES CCOC(=O)\C=C1/N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(=O)CC11CCCC1 Show InChI InChI=1S/C26H27N5O3/c1-2-34-24(33)15-22-26(13-5-6-14-26)16-23(32)31(22)17-18-9-11-19(12-10-18)20-7-3-4-8-21(20)25-27-29-30-28-25/h3-4,7-12,15H,2,5-6,13-14,16-17H2,1H3,(H,27,28,29,30)/b22-15-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem...				Bioorg Med Chem Lett 3: 369-374 (1993) Article DOI: 10.1016/S0960-894X(01)80914-8 BindingDB Entry DOI: 10.7270/Q20G3K2H
					More data for this Ligand-Target Pair