BDBM50282053 4-Amino-2-(1-aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]isoquinoline-1,3-dione::CHEMBL289126

SMILES: Nc1ccc2cccc3C(=O)N(C4CN5CCC4CC5)C(=O)c1c23

InChI Key: InChIKey=SELOZYYVDMLKPP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50282053 (4-Amino-2-(1-aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]...) Show SMILES Nc1ccc2cccc3C(=O)N(C4CN5CCC4CC5)C(=O)c1c23 |(5.72,-7.54,;4.39,-6.77,;3.04,-7.54,;1.71,-6.77,;1.71,-5.23,;.38,-4.46,;.38,-2.92,;1.71,-2.15,;3.04,-2.92,;4.37,-2.15,;4.37,-.61,;5.72,-2.92,;7.05,-2.15,;8.38,-2.92,;9.71,-2.15,;9.71,-.61,;8.38,.16,;7.03,-.61,;7.8,-1.94,;8.89,-.85,;5.72,-4.46,;7.05,-5.23,;4.37,-5.23,;3.04,-4.46,)| Show InChI InChI=1S/C19H19N3O2/c20-14-5-4-12-2-1-3-13-16(12)17(14)19(24)22(18(13)23)15-10-21-8-6-11(15)7-9-21/h1-5,11,15H,6-10,20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]-BRL-43694 displacement.				Bioorg Med Chem Lett 3: 1555-1558 (1993) Article DOI: 10.1016/S0960-894X(00)80017-7 BindingDB Entry DOI: 10.7270/Q2J38SHW
					More data for this Ligand-Target Pair