BDBM50282240 CHEMBL288691::Lithium; 2-[4-(2-butyl-5-hydroxymethyl-imidazol-1-ylmethyl)-indol-1-yl]-benzoate
SMILES: CCCCc1ncc(CO)n1Cc1cccc2n(ccc12)-c1ccccc1C([O-])=O
InChI Key: InChIKey=AJYPLEHQCRHUIZ-UHFFFAOYSA-M
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin II AT1B (RAT) | BDBM50282240 (CHEMBL288691 | Lithium; 2-[4-(2-butyl-5-hydroxymet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | Bioorg Med Chem Lett 4: 145-150 (1994) Article DOI: 10.1016/S0960-894X(01)81137-9 BindingDB Entry DOI: 10.7270/Q2V988KF | |||||||||||
More data for this Ligand-Target Pair |