BDBM50282602 (3S,4S)-5-Cyclohexyl-3-hydroxy-4-((S)-4-methyl-2-{(S)-2-[3-(2-oxo-2,3-dihydro-pyrido[2,3-b][1,4]thiazin-1-yl)-propionylamino]-3-phenyl-propionylamino}-pentanoylamino)-pentanoic acid (3-imidazol-1-yl-propyl)-amide::CHEMBL24423

SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CCN1C(=O)CSc2ncccc12)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CC(=O)NCCCn1ccnc1

InChI Key: InChIKey=NSORIBLJGXKBTF-RRNXAADDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50282602 ((3S,4S)-5-Cyclohexyl-3-hydroxy-4-((S)-4-methyl-2-{...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CCN1C(=O)CSc2ncccc12)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CC(=O)NCCCn1ccnc1 Show InChI InChI=1S/C42H58N8O6S/c1-29(2)23-33(40(55)47-32(24-30-11-5-3-6-12-30)36(51)26-38(53)44-18-10-20-49-22-19-43-28-49)48-41(56)34(25-31-13-7-4-8-14-31)46-37(52)16-21-50-35-15-9-17-45-42(35)57-27-39(50)54/h4,7-9,13-15,17,19,22,28-30,32-34,36,51H,3,5-6,10-12,16,18,20-21,23-27H2,1-2H3,(H,44,53)(H,46,52)(H,47,55)(H,48,56)/t32-,33-,34-,36-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human plasma renin at pH 65.0				Bioorg Med Chem Lett 4: 1291-1296 (1994) Article DOI: 10.1016/S0960-894X(01)80347-4 BindingDB Entry DOI: 10.7270/Q2C8297D
					More data for this Ligand-Target Pair