BDBM50282610 (3S,4S)-5-Cyclohexyl-3-hydroxy-4-((S)-4-methyl-2-{(S)-2-[2-(3-oxo-2,3-dihydro-pyrido[4,3-b][1,4]thiazin-4-yl)-acetylamino]-3-phenyl-propionylamino}-pentanoylamino)-pentanoic acid (3-imidazol-1-yl-propyl)-amide::CHEMBL436543

SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN1C(=O)CSc2ccncc12)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CC(=O)NCCCn1ccnc1

InChI Key: InChIKey=WFZIEOXNRIZYBW-TUCRWICHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50282610 ((3S,4S)-5-Cyclohexyl-3-hydroxy-4-((S)-4-methyl-2-{...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN1C(=O)CSc2ccncc12)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CC(=O)NCCCn1ccnc1 Show InChI InChI=1S/C41H56N8O6S/c1-28(2)20-32(40(54)46-31(21-29-10-5-3-6-11-29)35(50)23-37(51)44-15-9-18-48-19-17-43-27-48)47-41(55)33(22-30-12-7-4-8-13-30)45-38(52)25-49-34-24-42-16-14-36(34)56-26-39(49)53/h4,7-8,12-14,16-17,19,24,27-29,31-33,35,50H,3,5-6,9-11,15,18,20-23,25-26H2,1-2H3,(H,44,51)(H,45,52)(H,46,54)(H,47,55)/t31-,32-,33-,35-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human plasma renin at pH 65.0				Bioorg Med Chem Lett 4: 1291-1296 (1994) Article DOI: 10.1016/S0960-894X(01)80347-4 BindingDB Entry DOI: 10.7270/Q2C8297D
					More data for this Ligand-Target Pair