BDBM50282847 (2S,4S)-4-Cyclohexyl-1-[(S)-2-((S)-2-mercaptomethyl-3-phenyl-propionylamino)-propionyl]-pyrrolidine-2-carboxylic acid::CHEMBL422403

SMILES: C[C@H](NC(=O)[C@@H](CS)Cc1ccccc1)C(=O)N1C[C@@H](C[C@H]1C(O)=O)C1CCCCC1

InChI Key: InChIKey=ZWYUEFIHPSYMKL-ZXNZYJFHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50282847 ((2S,4S)-4-Cyclohexyl-1-[(S)-2-((S)-2-mercaptomethy...) Show SMILES C[C@H](NC(=O)[C@@H](CS)Cc1ccccc1)C(=O)N1C[C@@H](C[C@H]1C(O)=O)C1CCCCC1 Show InChI InChI=1S/C24H34N2O4S/c1-16(25-22(27)20(15-31)12-17-8-4-2-5-9-17)23(28)26-14-19(13-21(26)24(29)30)18-10-6-3-7-11-18/h2,4-5,8-9,16,18-21,31H,3,6-7,10-15H2,1H3,(H,25,27)(H,29,30)/t16-,19+,20+,21-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrate				Bioorg Med Chem Lett 4: 1783-1788 (1994) Article DOI: 10.1016/S0960-894X(01)80371-1 BindingDB Entry DOI: 10.7270/Q2Z3204W
					More data for this Ligand-Target Pair
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50282847 ((2S,4S)-4-Cyclohexyl-1-[(S)-2-((S)-2-mercaptomethy...) Show SMILES C[C@H](NC(=O)[C@@H](CS)Cc1ccccc1)C(=O)N1C[C@@H](C[C@H]1C(O)=O)C1CCCCC1 Show InChI InChI=1S/C24H34N2O4S/c1-16(25-22(27)20(15-31)12-17-8-4-2-5-9-17)23(28)26-14-19(13-21(26)24(29)30)18-10-6-3-7-11-18/h2,4-5,8-9,16,18-21,31H,3,6-7,10-15H2,1H3,(H,25,27)(H,29,30)/t16-,19+,20+,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrate				Bioorg Med Chem Lett 4: 1783-1788 (1994) Article DOI: 10.1016/S0960-894X(01)80371-1 BindingDB Entry DOI: 10.7270/Q2Z3204W
					More data for this Ligand-Target Pair