BDBM50283548 1-{(5S,8S)-3-Butyl-1-chloro-5-[2'-(2H-tetrazol-5-yl)-biphenyl-4-yl]-5,6,7,8-tetrahydro-imidazo[1,5-a]pyridin-8-yl}-pyrrolidine-2,5-dione::CHEMBL315219

SMILES: CCCCc1nc(Cl)c2[C@H](CC[C@@H](c3ccc(cc3)-c3ccccc3-c3nnn[nH]3)n12)N1C(=O)CCC1=O

InChI Key: InChIKey=JRCVIBWLJIQPOI-VXKWHMMOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50283548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50283548 (1-{(5S,8S)-3-Butyl-1-chloro-5-[2'-(2H-tetrazol-5-y...) Show SMILES CCCCc1nc(Cl)c2[C@H](CC[C@@H](c3ccc(cc3)-c3ccccc3-c3nnn[nH]3)n12)N1C(=O)CCC1=O Show InChI InChI=1S/C28H28ClN7O2/c1-2-3-8-23-30-27(29)26-22(36-24(37)15-16-25(36)38)14-13-21(35(23)26)18-11-9-17(10-12-18)19-6-4-5-7-20(19)28-31-33-34-32-28/h4-7,9-12,21-22H,2-3,8,13-16H2,1H3,(H,31,32,33,34)/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [125-I]-labeled angiotensin II binding to AT1 receptor in rat uterine membranes				Bioorg Med Chem Lett 4: 2591-2596 (1994) Article DOI: 10.1016/S0960-894X(01)80290-0 BindingDB Entry DOI: 10.7270/Q29Z94VB
					More data for this Ligand-Target Pair