BDBM50283582 2-(3-Carboxy-5-dicarboxymethoxy-phenoxy)-malonic acid::CHEMBL329115
SMILES: OC(=O)C(Oc1cc(OC(C(O)=O)C(O)=O)cc(c1)C(O)=O)C(O)=O
InChI Key: InChIKey=XGJMQFAIEPOUMO-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-enolpyruvylshikimate-3-phosphate synthase (Escherichia coli (strain K12)) | BDBM50283582 (2-(3-Carboxy-5-dicarboxymethoxy-phenoxy)-malonic a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Escherichia coli EPSP synthase | Bioorg Med Chem Lett 4: 2605-2608 (1994) Article DOI: 10.1016/S0960-894X(01)80293-6 BindingDB Entry DOI: 10.7270/Q25M666T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-enolpyruvylshikimate-3-phosphate synthase (Escherichia coli (strain K12)) | BDBM50283582 (2-(3-Carboxy-5-dicarboxymethoxy-phenoxy)-malonic a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against EPSP(5-enolpyruvylshikimate 3-phosphate) synthase in Escherichia coli. | Bioorg Med Chem Lett 6: 2853-2858 (1996) Article DOI: 10.1016/S0960-894X(96)00527-6 BindingDB Entry DOI: 10.7270/Q2833SJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-enolpyruvylshikimate-3-phosphate synthase (Escherichia coli (strain K12)) | BDBM50283582 (2-(3-Carboxy-5-dicarboxymethoxy-phenoxy)-malonic a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Escherichia coli EPSP synthase | Bioorg Med Chem Lett 4: 2605-2608 (1994) Article DOI: 10.1016/S0960-894X(01)80293-6 BindingDB Entry DOI: 10.7270/Q25M666T | |||||||||||
More data for this Ligand-Target Pair |