BDBM50283591 4-[2-Chloro-2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-2-ethyl-5,6,7,8-tetrahydro-quinoline::CHEMBL314859
SMILES: CCc1cc(OCc2ccc(c(Cl)c2)-c2ccccc2-c2nnn[nH]2)c2CCCCc2n1
InChI Key: InChIKey=KDRYYKNFANUHTJ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50283591 (4-[2-Chloro-2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for in vitro inhibition of specific binding of [I-125]AII to AT1 receptor in guinea pig adrenal membrane preparation | Bioorg Med Chem Lett 4: 2615-2620 (1994) Article DOI: 10.1016/S0960-894X(01)80295-X BindingDB Entry DOI: 10.7270/Q22J6BTX | |||||||||||
More data for this Ligand-Target Pair |