BDBM50283607 7-(2-Mercaptomethyl-3-phenyl-propionylamino)-heptanoic acid::CHEMBL328519
SMILES: OC(=O)CCCCCCNC(=O)C(CS)Cc1ccccc1
InChI Key: InChIKey=KJVKOEVEFLXJES-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat)) | BDBM50283607 (7-(2-Mercaptomethyl-3-phenyl-propionylamino)-hepta...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membrane | Bioorg Med Chem Lett 4: 2673-2676 (1994) Article DOI: 10.1016/S0960-894X(01)80694-6 BindingDB Entry DOI: 10.7270/Q2X34XXT | |||||||||||
More data for this Ligand-Target Pair |