BDBM50283612 (3S,5R)-4-(2-Mercaptomethyl-3-phenyl-propionylamino)-1-((S)-3-mercapto-2-methyl-propionyl)-pyrrolidine-2-carboxylic acid::CHEMBL91623
SMILES: C[C@H](CS)C(=O)N1C[C@@H](C[C@H]1C(O)=O)NC(=O)C(CS)Cc1ccccc1
InChI Key: InChIKey=BVEZVWDJQNJONB-OHRKKDJYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50283612 ((3S,5R)-4-(2-Mercaptomethyl-3-phenyl-propionylamin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition against angiotensin converting enzyme (ACE) | Bioorg Med Chem Lett 4: 2673-2676 (1994) Article DOI: 10.1016/S0960-894X(01)80694-6 BindingDB Entry DOI: 10.7270/Q2X34XXT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat)) | BDBM50283612 ((3S,5R)-4-(2-Mercaptomethyl-3-phenyl-propionylamin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 849 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membrane | Bioorg Med Chem Lett 4: 2673-2676 (1994) Article DOI: 10.1016/S0960-894X(01)80694-6 BindingDB Entry DOI: 10.7270/Q2X34XXT | |||||||||||
More data for this Ligand-Target Pair |