BDBM50283654 (S)-3-Biphenyl-4-yl-2-[(S)-3-(1H-imidazol-4-yl)-2-(phosphonomethyl-amino)-propionylamino]-propionic acid::CHEMBL315669

SMILES: OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NCP(O)(O)=O

InChI Key: InChIKey=LXMRJGDZPNJAFZ-PMACEKPBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ACEI-ACE2 (Homo sapiens (Human))	BDBM50283654 ((S)-3-Biphenyl-4-yl-2-[(S)-3-(1H-imidazol-4-yl)-2-...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NCP(O)(O)=O Show InChI InChI=1S/C22H25N4O6P/c27-21(19(25-14-33(30,31)32)11-18-12-23-13-24-18)26-20(22(28)29)10-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-9,12-13,19-20,25H,10-11,14H2,(H,23,24)(H,26,27)(H,28,29)(H2,30,31,32)/t19-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against angiotensin-converting enzyme				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50283654 ((S)-3-Biphenyl-4-yl-2-[(S)-3-(1H-imidazol-4-yl)-2-...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NCP(O)(O)=O Show InChI InChI=1S/C22H25N4O6P/c27-21(19(25-14-33(30,31)32)11-18-12-23-13-24-18)26-20(22(28)29)10-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-9,12-13,19-20,25H,10-11,14H2,(H,23,24)(H,26,27)(H,28,29)(H2,30,31,32)/t19-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against neutral endopeptidase				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair