BDBM50283655 (S)-3-Biphenyl-4-yl-2-[(S)-3-(4-chloro-phenyl)-2-(phosphonomethyl-amino)-propionylamino]-propionic acid::CHEMBL329464

SMILES: OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccc(Cl)cc1)NCP(O)(O)=O

InChI Key: InChIKey=VMBLGPAYYKVWDU-GOTSBHOMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ACEI-ACE2 (Homo sapiens (Human))	BDBM50283655 ((S)-3-Biphenyl-4-yl-2-[(S)-3-(4-chloro-phenyl)-2-(...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccc(Cl)cc1)NCP(O)(O)=O Show InChI InChI=1S/C25H26ClN2O6P/c26-21-12-8-18(9-13-21)14-22(27-16-35(32,33)34)24(29)28-23(25(30)31)15-17-6-10-20(11-7-17)19-4-2-1-3-5-19/h1-13,22-23,27H,14-16H2,(H,28,29)(H,30,31)(H2,32,33,34)/t22-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	473	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against angiotensin-converting enzyme				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50283655 ((S)-3-Biphenyl-4-yl-2-[(S)-3-(4-chloro-phenyl)-2-(...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccc(Cl)cc1)NCP(O)(O)=O Show InChI InChI=1S/C25H26ClN2O6P/c26-21-12-8-18(9-13-21)14-22(27-16-35(32,33)34)24(29)28-23(25(30)31)15-17-6-10-20(11-7-17)19-4-2-1-3-5-19/h1-13,22-23,27H,14-16H2,(H,28,29)(H,30,31)(H2,32,33,34)/t22-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against neutral endopeptidase				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair