BDBM50283660 (S)-3-Biphenyl-4-yl-2-[(S)-2-(carboxymethyl-amino)-3-methyl-pentanoylamino]-propionic acid::CHEMBL328737

SMILES: CC[C@H](C)C(NCC(O)=O)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key: InChIKey=OHEMLLQWDPOUER-BGNMZJEESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ACEI-ACE2 (Homo sapiens (Human))	BDBM50283660 ((S)-3-Biphenyl-4-yl-2-[(S)-2-(carboxymethyl-amino)...) Show SMILES CC[C@H](C)C(NCC(O)=O)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(O)=O Show InChI InChI=1S/C23H28N2O5/c1-3-15(2)21(24-14-20(26)27)22(28)25-19(23(29)30)13-16-9-11-18(12-10-16)17-7-5-4-6-8-17/h4-12,15,19,21,24H,3,13-14H2,1-2H3,(H,25,28)(H,26,27)(H,29,30)/t15-,19-,21?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against angiotensin-converting enzyme				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50283660 ((S)-3-Biphenyl-4-yl-2-[(S)-2-(carboxymethyl-amino)...) Show SMILES CC[C@H](C)C(NCC(O)=O)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(O)=O Show InChI InChI=1S/C23H28N2O5/c1-3-15(2)21(24-14-20(26)27)22(28)25-19(23(29)30)13-16-9-11-18(12-10-16)17-7-5-4-6-8-17/h4-12,15,19,21,24H,3,13-14H2,1-2H3,(H,25,28)(H,26,27)(H,29,30)/t15-,19-,21?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against neutral endopeptidase				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair