BDBM50283826 CHEMBL327496::N-tert-Butyl-2-{(3R,5S,7R)-3-[3-(3-fluoro-phenyl)-ureido]-2-oxo-7-phenyl-5-o-tolyl-azepan-1-yl}-acetamide

SMILES: Cc1ccccc1[C@H]1C[C@@H](NC(=O)Nc2cccc(F)c2)C(=O)N(CC(=O)NC(C)(C)C)[C@H](C1)c1ccccc1

InChI Key: InChIKey=RUXGBVNMEPICAJ-MLKSZZLFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50283826 (CHEMBL327496 | N-tert-Butyl-2-{(3R,5S,7R)-3-[3-(3-...) Show SMILES Cc1ccccc1[C@H]1C[C@@H](NC(=O)Nc2cccc(F)c2)C(=O)N(CC(=O)NC(C)(C)C)[C@H](C1)c1ccccc1 Show InChI InChI=1S/C32H37FN4O3/c1-21-11-8-9-16-26(21)23-17-27(35-31(40)34-25-15-10-14-24(33)19-25)30(39)37(20-29(38)36-32(2,3)4)28(18-23)22-12-6-5-7-13-22/h5-16,19,23,27-28H,17-18,20H2,1-4H3,(H,36,38)(H2,34,35,40)/t23-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against cholecystokinin-B (CCK-B) receptor in cortex of male hartley guinea pig.				Bioorg Med Chem Lett 4: 2877-2882 (1994) Article DOI: 10.1016/S0960-894X(01)80832-5 BindingDB Entry DOI: 10.7270/Q24B318F
					More data for this Ligand-Target Pair
Cholecystokinin A receptor (Cavia porcellus)	BDBM50283826 (CHEMBL327496 | N-tert-Butyl-2-{(3R,5S,7R)-3-[3-(3-...) Show SMILES Cc1ccccc1[C@H]1C[C@@H](NC(=O)Nc2cccc(F)c2)C(=O)N(CC(=O)NC(C)(C)C)[C@H](C1)c1ccccc1 Show InChI InChI=1S/C32H37FN4O3/c1-21-11-8-9-16-26(21)23-17-27(35-31(40)34-25-15-10-14-24(33)19-25)30(39)37(20-29(38)36-32(2,3)4)28(18-23)22-12-6-5-7-13-22/h5-16,19,23,27-28H,17-18,20H2,1-4H3,(H,36,38)(H2,34,35,40)/t23-,27+,28+/m0/s1	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against cholecystokinin-A (CCK-A) receptor in pancreas of guinea pig.				Bioorg Med Chem Lett 4: 2877-2882 (1994) Article DOI: 10.1016/S0960-894X(01)80832-5 BindingDB Entry DOI: 10.7270/Q24B318F
					More data for this Ligand-Target Pair