BDBM50283843 CHEMBL320821::N-(2-Chloro-phenyl)-2-[(3R,5S,7R)-2-oxo-7-phenyl-5-o-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide
SMILES: Cc1cccc(NC(=O)N[C@@H]2C[C@@H](C[C@@H](N(CC(=O)Nc3ccccc3Cl)C2=O)c2ccccc2)c2ccccc2C)c1
InChI Key: InChIKey=GQFWYWXTSTVXPK-OODHRNECSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50283843 (CHEMBL320821 | N-(2-Chloro-phenyl)-2-[(3R,5S,7R)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against cholecystokinin-B (CCK-B) receptor in cortex of male hartley guinea pig. | Bioorg Med Chem Lett 4: 2877-2882 (1994) Article DOI: 10.1016/S0960-894X(01)80832-5 BindingDB Entry DOI: 10.7270/Q24B318F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin A receptor (Cavia porcellus) | BDBM50283843 (CHEMBL320821 | N-(2-Chloro-phenyl)-2-[(3R,5S,7R)-2...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against cholecystokinin-A (CCK-A) receptor in pancreas of guinea pig. | Bioorg Med Chem Lett 4: 2877-2882 (1994) Article DOI: 10.1016/S0960-894X(01)80832-5 BindingDB Entry DOI: 10.7270/Q24B318F | |||||||||||
More data for this Ligand-Target Pair |