BDBM50284800 ((5R,6S)-9-Bromo-6-ethyl-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyrido[1,2,3-de]quinoxalin-5-yl)-acetic acid::CHEMBL289151
SMILES: CC[C@H]1Cc2cc(Br)cc3[nH]c(=O)c(=O)n([C@@H]1CC(O)=O)c23
InChI Key: InChIKey=VAKWFAARKWMFQB-WRWORJQWSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50284800 (((5R,6S)-9-Bromo-6-ethyl-2,3-dioxo-2,3,6,7-tetrahy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity measured by using [3H]5,7-dichlorokynurenic acid (DCKA) for the glycine binding site of NMDA receptor | Bioorg Med Chem Lett 5: 1527-1532 (1995) Article DOI: 10.1016/0960-894X(95)00243-M BindingDB Entry DOI: 10.7270/Q2K35TKC | |||||||||||
More data for this Ligand-Target Pair |