BDBM50284813 ((S)-9-Chloro-6-methyl-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyrido[1,2,3-de]quinoxalin-5-yl)-acetic acid::CHEMBL40730
SMILES: C[C@H]1Cc2cc(Cl)cc3[nH]c(=O)c(=O)n(C1CC(O)=O)c23
InChI Key: InChIKey=OQRLRDJMCPBHGC-UOQJWNSWSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50284813 (((S)-9-Chloro-6-methyl-2,3-dioxo-2,3,6,7-tetrahydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity for the glycine binding site of the NMDA receptor using [3H]- 5,7- dichloro -kynurenic acid as radio-ligand | Bioorg Med Chem Lett 5: 1533-1536 (1995) Article DOI: 10.1016/0960-894X(95)00244-N BindingDB Entry DOI: 10.7270/Q2FB52WG | |||||||||||
More data for this Ligand-Target Pair |