null

SMILES: CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(O[C@H](C)[C@@H](C)O1)c1ccccc1

InChI Key: InChIKey=LUBRBIXAPOXZGB-RTBURBONSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50284874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50284874 (1-(2,6-Diisopropyl-phenyl)-3-((4R,5R)-4,5-dimethyl...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(O[C@H](C)[C@@H](C)O1)c1ccccc1 Show InChI InChI=1S/C25H34N2O3/c1-16(2)21-13-10-14-22(17(3)4)23(21)27-24(28)26-15-25(20-11-8-7-9-12-20)29-18(5)19(6)30-25/h7-14,16-19H,15H2,1-6H3,(H2,26,27,28)/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against acylcoA: cholesterol acyltransferase (ACAT) in microsomes from cholesterol-fed rabbit thoracic aorta				Bioorg Med Chem Lett 5: 1581-1586 (1995) Article DOI: 10.1016/0960-894X(95)00275-X BindingDB Entry DOI: 10.7270/Q2222TPK
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50284874 (1-(2,6-Diisopropyl-phenyl)-3-((4R,5R)-4,5-dimethyl...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(O[C@H](C)[C@@H](C)O1)c1ccccc1 Show InChI InChI=1S/C25H34N2O3/c1-16(2)21-13-10-14-22(17(3)4)23(21)27-24(28)26-15-25(20-11-8-7-9-12-20)29-18(5)19(6)30-25/h7-14,16-19H,15H2,1-6H3,(H2,26,27,28)/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against acylcoA: cholesterol acyltransferase (ACAT) in microsomes from cholesterol-fed rabbit intestinal mucosa				Bioorg Med Chem Lett 5: 1581-1586 (1995) Article DOI: 10.1016/0960-894X(95)00275-X BindingDB Entry DOI: 10.7270/Q2222TPK
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50284874 (1-(2,6-Diisopropyl-phenyl)-3-((4R,5R)-4,5-dimethyl...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(O[C@H](C)[C@@H](C)O1)c1ccccc1 Show InChI InChI=1S/C25H34N2O3/c1-16(2)21-13-10-14-22(17(3)4)23(21)27-24(28)26-15-25(20-11-8-7-9-12-20)29-18(5)19(6)30-25/h7-14,16-19H,15H2,1-6H3,(H2,26,27,28)/t18-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against acylcoA: cholesterol acyltransferase (ACAT) in microsomes from monkey liver				Bioorg Med Chem Lett 5: 1581-1586 (1995) Article DOI: 10.1016/0960-894X(95)00275-X BindingDB Entry DOI: 10.7270/Q2222TPK
					More data for this Ligand-Target Pair