BDBM50284905 (1-{(R)-1-{3-[(E)-2-(5,6-Difluoro-benzothiazol-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid::CHEMBL42051

SMILES: CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2nc3cc(F)c(F)cc3s2)c1

InChI Key: InChIKey=HWCOCJJSVWELFF-OXIVNLASSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284905 ((1-{(R)-1-{3-[(E)-2-(5,6-Difluoro-benzothiazol-2-y...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2nc3cc(F)c(F)cc3s2)c1 Show InChI InChI=1S/C33H33F2NO3S2/c1-32(2,39)24-9-4-3-7-22(24)11-12-28(40-20-33(14-15-33)19-31(37)38)23-8-5-6-21(16-23)10-13-30-36-27-17-25(34)26(35)18-29(27)41-30/h3-10,13,16-18,28,39H,11-12,14-15,19-20H2,1-2H3,(H,37,38)/b13-10+/t28-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair