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BDBM50284944 ((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid benzyl ester::CHEMBL298965

SMILES: O=C(N[C@@H](Cc1ccccc1)[C@H]1CO1)OCc1ccccc1

InChI Key: InChIKey=DURMMNMFHRIMJD-DLBZAZTESA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50284944   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin (B and K)


(Homo sapiens (Human))
BDBM50284944
PNG
(((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid ...)
Show SMILES O=C(N[C@@H](Cc1ccccc1)[C@H]1CO1)OCc1ccccc1
Show InChI InChI=1S/C18H19NO3/c20-18(22-12-15-9-5-2-6-10-15)19-16(17-13-21-17)11-14-7-3-1-4-8-14/h1-10,16-17H,11-13H2,(H,19,20)/t16-,17+/m0/s1
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Article
0.0870n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL




Bioorg Med Chem Lett 5: 1767-1772 (1995)


Article DOI: 10.1016/0960-894X(95)00312-H
BindingDB Entry DOI: 10.7270/Q2MW2H4X
More data for this
Ligand-Target Pair
Papain


(Carica papaya)
BDBM50284944
PNG
(((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid ...)
Show SMILES O=C(N[C@@H](Cc1ccccc1)[C@H]1CO1)OCc1ccccc1
Show InChI InChI=1S/C18H19NO3/c20-18(22-12-15-9-5-2-6-10-15)19-16(17-13-21-17)11-14-7-3-1-4-8-14/h1-10,16-17H,11-13H2,(H,19,20)/t16-,17+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
0.208n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL




Bioorg Med Chem Lett 5: 1767-1772 (1995)


Article DOI: 10.1016/0960-894X(95)00312-H
BindingDB Entry DOI: 10.7270/Q2MW2H4X
More data for this
Ligand-Target Pair
Cathepsin (B and K)


(Homo sapiens (Human))
BDBM50284944
PNG
(((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid ...)
Show SMILES O=C(N[C@@H](Cc1ccccc1)[C@H]1CO1)OCc1ccccc1
Show InChI InChI=1S/C18H19NO3/c20-18(22-12-15-9-5-2-6-10-15)19-16(17-13-21-17)11-14-7-3-1-4-8-14/h1-10,16-17H,11-13H2,(H,19,20)/t16-,17+/m0/s1
PDB
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Patents

Article
3.67E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic parameter of the compound (Ki mM) was evaluated for the inactivation of cathepsin B


Bioorg Med Chem Lett 5: 1767-1772 (1995)


Article DOI: 10.1016/0960-894X(95)00312-H
BindingDB Entry DOI: 10.7270/Q2MW2H4X
More data for this
Ligand-Target Pair
Papain


(Carica papaya)
BDBM50284944
PNG
(((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid ...)
Show SMILES O=C(N[C@@H](Cc1ccccc1)[C@H]1CO1)OCc1ccccc1
Show InChI InChI=1S/C18H19NO3/c20-18(22-12-15-9-5-2-6-10-15)19-16(17-13-21-17)11-14-7-3-1-4-8-14/h1-10,16-17H,11-13H2,(H,19,20)/t16-,17+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
5.74E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic parameter of the compound (Ki mM) was evaluated for the inactivation of papain


Bioorg Med Chem Lett 5: 1767-1772 (1995)


Article DOI: 10.1016/0960-894X(95)00312-H
BindingDB Entry DOI: 10.7270/Q2MW2H4X
More data for this
Ligand-Target Pair