BDBM50285003 3,10-dimethoxy-17-phenethyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one; with HBr::CHEMBL545208
SMILES: COc1cccc2CC3N(CCc4ccccc4)CC[C@@]4(CC(=O)CC[C@@]34OC)c12
InChI Key: InChIKey=NWFRYEOZMKEEMS-NYJWAPBASA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (GUINEA PIG) | BDBM50285003 (3,10-dimethoxy-17-phenethyl-17-azatetracyclo[7.5.3...) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity by its ability to displace [3H]DAMGO from mu receptor in homogenates of guinea pig brain | Bioorg Med Chem Lett 5: 1923-1926 (1995) Article DOI: 10.1016/0960-894X(95)00325-N BindingDB Entry DOI: 10.7270/Q2FX79XF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50285003 (3,10-dimethoxy-17-phenethyl-17-azatetracyclo[7.5.3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity by its ability to displace [3H]DPDPE from delta receptor in homogenates of guinea pig brain | Bioorg Med Chem Lett 5: 1923-1926 (1995) Article DOI: 10.1016/0960-894X(95)00325-N BindingDB Entry DOI: 10.7270/Q2FX79XF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50285003 (3,10-dimethoxy-17-phenethyl-17-azatetracyclo[7.5.3...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity by its ability to displace [3H]-U-69,593 from kappa receptor in homogenates of guinea pig brain | Bioorg Med Chem Lett 5: 1923-1926 (1995) Article DOI: 10.1016/0960-894X(95)00325-N BindingDB Entry DOI: 10.7270/Q2FX79XF | |||||||||||
More data for this Ligand-Target Pair |