BDBM50285012 CHEMBL301418::N-tert-Butyl-2-((3R,5R)-8-methyl-2-oxo-5-phenyl-3-{3-[3-(1H-tetrazol-5-yl)-phenyl]-ureido}-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-acetamide
SMILES: Cc1ccc2[C@H](C[C@@H](NC(=O)Nc3cccc(c3)-c3nnn[nH]3)C(=O)N(CC(=O)NC(C)(C)C)c2c1)c1ccccc1
InChI Key: InChIKey=MQIOWUHVKXZQPM-JWQCQUIFSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50285012 (CHEMBL301418 | N-tert-Butyl-2-((3R,5R)-8-methyl-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.810 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding activity towards cholecystokinin-B (CCK-B) receptor in guinea pig cortex | Bioorg Med Chem Lett 5: 1933-1936 (1995) Article DOI: 10.1016/0960-894X(95)00327-P BindingDB Entry DOI: 10.7270/Q22Z15H2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin A receptor (Cavia porcellus) | BDBM50285012 (CHEMBL301418 | N-tert-Butyl-2-((3R,5R)-8-methyl-2-...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding activity towards cholecystokinin-A (CCK-A) receptor in guinea pig pancreas | Bioorg Med Chem Lett 5: 1933-1936 (1995) Article DOI: 10.1016/0960-894X(95)00327-P BindingDB Entry DOI: 10.7270/Q22Z15H2 | |||||||||||
More data for this Ligand-Target Pair |