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SMILES: COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C[C@H]1NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C

InChI Key: InChIKey=FLWHVVRSAYNEGS-VQTJNVASSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285040   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50285040
PNG
((3S,4R)-3-tert-Butoxycarbonylamino-4-(3-cyclopenty...)
Show SMILES COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C[C@H]1NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C
Show InChI InChI=1S/C26H40N2O6/c1-25(2,3)33-23(29)27-20-16-28(24(30)34-26(4,5)6)15-19(20)17-12-13-21(31-7)22(14-17)32-18-10-8-9-11-18/h12-14,18-20H,8-11,15-16H2,1-7H3,(H,27,29)/t19-,20+/m0/s1
PDB

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Similars
Article
 1.57E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)

Bioorg Med Chem Lett 5: 1977-1982 (1995)


Article DOI: 10.1016/0960-894X(95)00336-R
BindingDB Entry DOI: 10.7270/Q2PN95MX
More data for this
Ligand-Target Pair