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BDBM50285041 CHEMBL301053::methyl 3-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)-(3S,4R)-tetrahydro-1H-1-pyrrolecarboxylate

SMILES: COC(=O)N1C[C@@H](C#N)[C@@H](C1)c1ccc(OC)c(OC2CCCC2)c1

InChI Key: InChIKey=LITCGJWHJXCYGN-ZBFHGGJFSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285041   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50285041
PNG
(CHEMBL301053 | methyl 3-cyano-4-(3-cyclopentyloxy-...)
Show SMILES COC(=O)N1C[C@@H](C#N)[C@@H](C1)c1ccc(OC)c(OC2CCCC2)c1
Show InChI InChI=1S/C19H24N2O4/c1-23-17-8-7-13(9-18(17)25-15-5-3-4-6-15)16-12-21(19(22)24-2)11-14(16)10-20/h7-9,14-16H,3-6,11-12H2,1-2H3/t14-,16+/m1/s1
PDB

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UniProtKB/TrEMBL

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PC sid
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Similars
Article
 80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)

Bioorg Med Chem Lett 5: 1977-1982 (1995)


Article DOI: 10.1016/0960-894X(95)00336-R
BindingDB Entry DOI: 10.7270/Q2PN95MX
More data for this
Ligand-Target Pair