BDBM50285043 CHEMBL61727::methyl 4-(3-cyclopentyloxy-4-methoxyphenyl)-1-formyl-(3S,4R)-tetrahydro-1H-3-pyrrolecarboxylate

SMILES: COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC2CCCC2)c1)C=O

InChI Key: InChIKey=GJNGWOXXNOTIEU-JKSUJKDBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285043   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50285043 (CHEMBL61727 | methyl 4-(3-cyclopentyloxy-4-methoxy...) Show SMILES COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC2CCCC2)c1)C=O Show InChI InChI=1S/C19H25NO5/c1-23-17-8-7-13(9-18(17)25-14-5-3-4-6-14)15-10-20(12-21)11-16(15)19(22)24-2/h7-9,12,14-16H,3-6,10-11H2,1-2H3/t15-,16+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)				Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX
					More data for this Ligand-Target Pair