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BDBM50285053 1-(tert-butyl) 3-methyl 4-(3,4-dimethoxyphenyl)-(3S,4R)-tetrahydro-1H-1,3-pyrroledicarboxylate::CHEMBL60217

SMILES: COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC)c1)C(=O)OC(C)(C)C

InChI Key: InChIKey=IRLOZYMIVQBQPA-UONOGXRCSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285053   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50285053
PNG
(1-(tert-butyl) 3-methyl 4-(3,4-dimethoxyphenyl)-(3...)
Show SMILES COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC)c1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C19H27NO6/c1-19(2,3)26-18(22)20-10-13(14(11-20)17(21)25-6)12-7-8-15(23-4)16(9-12)24-5/h7-9,13-14H,10-11H2,1-6H3/t13-,14+/m0/s1
PDB

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Similars
Article
 1.20E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)

Bioorg Med Chem Lett 5: 1977-1982 (1995)


Article DOI: 10.1016/0960-894X(95)00336-R
BindingDB Entry DOI: 10.7270/Q2PN95MX
More data for this
Ligand-Target Pair