BDBM50285056 CHEMBL61284::methyl 1-amino(thioxo)methyl-4-(3-cyclopentyloxy-4-methoxyphenyl)-(3S,4R)-tetrahydro-1H-3-pyrrolecarboxylate
SMILES: COC(=O)[C@@H]1CN(C[C@H]1c1ccc(OC)c(OC2CCCC2)c1)C(N)=S
InChI Key: InChIKey=VUVAXWZQOZIXEJ-LSDHHAIUSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50285056 (CHEMBL61284 | methyl 1-amino(thioxo)methyl-4-(3-cy...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB) | Bioorg Med Chem Lett 5: 1977-1982 (1995) Article DOI: 10.1016/0960-894X(95)00336-R BindingDB Entry DOI: 10.7270/Q2PN95MX | |||||||||||
More data for this Ligand-Target Pair |