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BDBM50285061 CHEMBL61856::tert-butyl 3-carbamoyl-4-(3-cyclopentyloxy-4-methoxyphenyl)-(3S,4R)-tetrahydro-1H-1-pyrrolecarboxylate

SMILES: COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C[C@H]1C(N)=O)C(=O)OC(C)(C)C

InChI Key: InChIKey=YJJLYWUWBVCWPH-DLBZAZTESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285061   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50285061
PNG
(CHEMBL61856 | tert-butyl 3-carbamoyl-4-(3-cyclopen...)
Show SMILES COc1ccc(cc1OC1CCCC1)[C@@H]1CN(C[C@H]1C(N)=O)C(=O)OC(C)(C)C
Show InChI InChI=1S/C22H32N2O5/c1-22(2,3)29-21(26)24-12-16(17(13-24)20(23)25)14-9-10-18(27-4)19(11-14)28-15-7-5-6-8-15/h9-11,15-17H,5-8,12-13H2,1-4H3,(H2,23,25)/t16-,17+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
190n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)


Bioorg Med Chem Lett 5: 1977-1982 (1995)


Article DOI: 10.1016/0960-894X(95)00336-R
BindingDB Entry DOI: 10.7270/Q2PN95MX
More data for this
Ligand-Target Pair