BDBM50285079 4-Methoxy-3-((S)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ylmethyl)-benzene-1,2-diol::CHEMBL64152
SMILES: COc1ccc(O)c(O)c1CC1=C(C)CCC2C(C)(C)CCC[C@]12C
InChI Key: InChIKey=UWJFOBFXVGMJMW-AVKWCDSFSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50285079 (4-Methoxy-3-((S)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for Cholesteryl ester transfer protein (CETP) inhibition by CETP-SPA assay | Bioorg Med Chem Lett 5: 605-610 (1995) Article DOI: 10.1016/0960-894X(95)00081-4 BindingDB Entry DOI: 10.7270/Q20R9PWJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50285079 (4-Methoxy-3-((S)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for CETP inhibition by a precipitation method to separate lipoproteins after incubation of radiolabeled HDL with LDL and CETP. | Bioorg Med Chem Lett 5: 605-610 (1995) Article DOI: 10.1016/0960-894X(95)00081-4 BindingDB Entry DOI: 10.7270/Q20R9PWJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50285079 (4-Methoxy-3-((S)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Cholesterol ester transfer protein (CETP) | Bioorg Med Chem Lett 5: 2005-2010 (1995) Article DOI: 10.1016/0960-894X(95)00342-Q BindingDB Entry DOI: 10.7270/Q2F47P39 | |||||||||||
More data for this Ligand-Target Pair |