BDBM50285087 (R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzoylamino)-pyrrolidin-3-ylcarbamoyl]-benzoyl}-3-hydroxy-benzoic acid::CHEMBL59677

SMILES: OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1

InChI Key: InChIKey=STEGBXHZVWLLAP-IAGOWNOFSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50285087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C, eta (Homo sapiens (Human))	BDBM50285087 ((R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzo...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C26H23N3O9/c30-14-6-4-12(5-7-14)24(35)28-16-10-27-11-17(16)29-25(36)13-8-19(32)22(20(33)9-13)23(34)21-15(26(37)38)2-1-3-18(21)31/h1-9,16-17,27,30-33H,10-11H2,(H,28,35)(H,29,36)(H,37,38)/t16-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C eta				Bioorg Med Chem Lett 5: 2015-2020 (1995) Article DOI: 10.1016/0960-894X(95)00344-S BindingDB Entry DOI: 10.7270/Q29C6XD1
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50285087 ((R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzo...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C26H23N3O9/c30-14-6-4-12(5-7-14)24(35)28-16-10-27-11-17(16)29-25(36)13-8-19(32)22(20(33)9-13)23(34)21-15(26(37)38)2-1-3-18(21)31/h1-9,16-17,27,30-33H,10-11H2,(H,28,35)(H,29,36)(H,37,38)/t16-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta 2				Bioorg Med Chem Lett 5: 2015-2020 (1995) Article DOI: 10.1016/0960-894X(95)00344-S BindingDB Entry DOI: 10.7270/Q29C6XD1
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50285087 ((R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzo...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C26H23N3O9/c30-14-6-4-12(5-7-14)24(35)28-16-10-27-11-17(16)29-25(36)13-8-19(32)22(20(33)9-13)23(34)21-15(26(37)38)2-1-3-18(21)31/h1-9,16-17,27,30-33H,10-11H2,(H,28,35)(H,29,36)(H,37,38)/t16-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C alpha				Bioorg Med Chem Lett 5: 2015-2020 (1995) Article DOI: 10.1016/0960-894X(95)00344-S BindingDB Entry DOI: 10.7270/Q29C6XD1
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50285087 ((R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzo...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C26H23N3O9/c30-14-6-4-12(5-7-14)24(35)28-16-10-27-11-17(16)29-25(36)13-8-19(32)22(20(33)9-13)23(34)21-15(26(37)38)2-1-3-18(21)31/h1-9,16-17,27,30-33H,10-11H2,(H,28,35)(H,29,36)(H,37,38)/t16-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C beta 1				Bioorg Med Chem Lett 5: 2015-2020 (1995) Article DOI: 10.1016/0960-894X(95)00344-S BindingDB Entry DOI: 10.7270/Q29C6XD1
					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM50285087 ((R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzo...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C26H23N3O9/c30-14-6-4-12(5-7-14)24(35)28-16-10-27-11-17(16)29-25(36)13-8-19(32)22(20(33)9-13)23(34)21-15(26(37)38)2-1-3-18(21)31/h1-9,16-17,27,30-33H,10-11H2,(H,28,35)(H,29,36)(H,37,38)/t16-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C epsilon				Bioorg Med Chem Lett 5: 2015-2020 (1995) Article DOI: 10.1016/0960-894X(95)00344-S BindingDB Entry DOI: 10.7270/Q29C6XD1
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50285087 ((R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzo...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C26H23N3O9/c30-14-6-4-12(5-7-14)24(35)28-16-10-27-11-17(16)29-25(36)13-8-19(32)22(20(33)9-13)23(34)21-15(26(37)38)2-1-3-18(21)31/h1-9,16-17,27,30-33H,10-11H2,(H,28,35)(H,29,36)(H,37,38)/t16-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C delta				Bioorg Med Chem Lett 5: 2015-2020 (1995) Article DOI: 10.1016/0960-894X(95)00344-S BindingDB Entry DOI: 10.7270/Q29C6XD1
					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50285087 ((R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzo...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C26H23N3O9/c30-14-6-4-12(5-7-14)24(35)28-16-10-27-11-17(16)29-25(36)13-8-19(32)22(20(33)9-13)23(34)21-15(26(37)38)2-1-3-18(21)31/h1-9,16-17,27,30-33H,10-11H2,(H,28,35)(H,29,36)(H,37,38)/t16-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C gamma				Bioorg Med Chem Lett 5: 2015-2020 (1995) Article DOI: 10.1016/0960-894X(95)00344-S BindingDB Entry DOI: 10.7270/Q29C6XD1
					More data for this Ligand-Target Pair
Protein kinase C (PKC) (Homo sapiens (Human))	BDBM50285087 ((R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzo...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C26H23N3O9/c30-14-6-4-12(5-7-14)24(35)28-16-10-27-11-17(16)29-25(36)13-8-19(32)22(20(33)9-13)23(34)21-15(26(37)38)2-1-3-18(21)31/h1-9,16-17,27,30-33H,10-11H2,(H,28,35)(H,29,36)(H,37,38)/t16-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Protein kinase C zeta				Bioorg Med Chem Lett 5: 2015-2020 (1995) Article DOI: 10.1016/0960-894X(95)00344-S BindingDB Entry DOI: 10.7270/Q29C6XD1
					More data for this Ligand-Target Pair